Evaluation of serum cystatinC concentrations in dogs infected with

Companion Animal
Posters Companion Animals
Evaluation of serum cystatinC
concentrations in dogs infected with
Dirofilaria immitis
Didem Pekmezci Assoc.
Prof., DVM, Ph.D.; Murat
Guzel Prof., DVM, Ph.D.;
Alparslan Yildirim Prof.,
DVM, Ph.D.; Gulay Ciftci
Assoc. Prof., DVM, Ph.D.;
Zafer Pekmezci Assoc. Prof.,
DVM, Ph.D.; Mehmet
Tutuncu Prof., DVM, Ph.D.;
Abdullah Inci Prof., DVM,
Ph.D.;
To assess glomerular filtration rate (GFR) in dogs naturally infected by D. immitis new
renal marker serum cystatinC (sCysC) was measured with canine CysC ELISA kit. Twenty
infected microfilaremic-seropositive and 20 amicrofilaremic and seronegative dogs
evaluated in the study. Serum urea and creatinine (sCre) concentrations were measured
in both groups. Mean sCysC concentrations in infected dogs were detected as 2.40
mg/L and 2.30 mg/L in controls. Mean serum urea 9.97 mmol/L and sCre 116.24 µmol/L
concentrations in infected and in the uninfected group detected as 11.92 mmol/L and
128.62 µmol/L, respectively. Including mean sCysC and sCre concentrations with mean
serum Urea:Cre ratio were not statistically differed between the groups. On the other
hand, serum urea concentrations were statistically differed between groups. Based on
the results of the present study, it is concluded that, sCysC concentrations seemed to be
not altered in dogs with D. immitis infection.
Department of Preclinical
Science, Faculty of
Veterinary Medicine,
University of Ondokuz
Mayis, Kurupelit Samsun
55139
Turkey
[email protected]
Abstracts | European Veterinary Conference Voorjaarsdagen 2016
www.voorjaarsdagen.eu