Yrd. Doç. Şükrü GÜLEÇ [email protected] sukrugulec@gmail

Yrd. Doç. Şükrü GÜLEÇ [email protected] sukrugulec@gmail

Yrd. Doç. Şükrü GÜLEÇ
[email protected]
[email protected]
Web Page: http://sukrugulec.wix.com/mylab
Tel: +90 232 750 6283
1. Adı Soyadı: Şükrü GÜLEÇ
2. Doğum Tarihi: 07.10.1980
3. Unvanı: Yardımcı Doçent
4. Öğrenim Durumu:
Derece
Alan
Lisans
Biyoloji
Y. Lisans
Biyoteknoloji
Doktora
Beslenme
Faks: +90 232 750 6196
Üniversite
Ankara Üniversitesi
Ankara Üniversitesi
Florida Üniversitesi
Yıl
2000-2004
2004-2006
2009-2013
5. Akademik Unvanlar:
2014- Yardımcı Doçent, İzmir Yüksek Teknoloji Enstitüsü Gıda Mühendisliği
2013-2014 Doktora Sonrası Araştırmacı, Florida Üniversitesi, Gıda ve Beslenme
Bölümü
2012-2013 Öğretim Görevlisi, Florida Üniversitesi, Gıda ve Beslenme Bölümü
2009-2012 Araştırma Görevlisi, Florida Üniversitesi, Gıda ve Beslenme Bölümü
2006-2008 Araştırmacı Biyolog,Florida Üniversitesi, Gıda ve Beslenme Bölümü
6. Yüksek Lisans ve Doktora Tezleri
6.1. Yüksek Lisans Tezi
“Türk Erken Miyokard İnfarktüslü Hastalarda Myocyte Faktör 2A (MEF2A) Gen
Varyantlarının İncelenmesi”
6.2. Doktora Tezi
“Physiological Role of Intestinal Copper Transporter Atp7a in Iron Metabolism.
7. Çalışma alanları
http://sukrugulec.wix.com/mylab
8. Yayınlar
8.1. Uluslararası hakemli dergilerde yayınlanan makaleler (SCI & SSCI &
Arts and Humanities)
1.Sukru Gulec, James F. Collins. Silencing of The Menkes Copper-Transporting Atpase (Atp7a) Gene Increases Cyclin D1
Protein Expressıon and Impairs Proliferation of Rat Intestinal Epithelial (IEC-6) Cells. 2014, J Trace Elem Med Biol. (İncelenme
aşamasında).
2.Sukru Gulec, James F. Collins. Molecular Mediators Governing Iron-Copper Interaction. 2014, The Annual Review of
Nutrition. (Kabul edildi).
3.Sukru Gulec, Gregory J. Anderson, James F. Collins. Mechanistic and Regulatory Aspects of Intestinal Iron Absorption.
2014, The American Journal of Physiology – Gastrointestinal and Liver Physiology (Kabul edildi).
4.Gulec S, Collins JF. Silencing the Menkes copper-transporting ATPase (Atp7a) gene in rat intestinal epithelial (IEC-6) cells
increases iron flux via transcriptional induction of ferroportin 1 (Fpn1). 2014, The American Journal of Nutrition.
5.Gulec S, Collins JF. Investigation of Iron Metabolism in Mice Expressing a Mutant Menke’s Copper Transporting ATPase
(Atp7a) Protein with Diminished Activity (Brindled; MoBr/y). 2013, PlosOne; Jun 11;8(6).
6.Afife Karabiyik, Erkan Yilmaz, Sukru Gulec, Ibrahim Haznedaroglu, Nejat Akar. Dual Diverse Dynamic Reversible Actions of
Ankaferd on EPCR and PAI-1 Inside Vascular Endothelial Cells With and Without LPS. 2012, Turkish Journal of
Hematology; DOI: 10.5152/tjh.2011.41.
7.Karabiyik A, Gulec S, Yilmaz E, Haznedaroglu I, Akar N. Reversible Protease-Activated Receptor I Downregulation Mediated
by Ankaferd Blood Stopper Inducible With Lipopolysaccharides Inside the Human Umbilical Vein Endothelial Cells. 2011, Clin
Appl Thromb Hemost; 17(6);E165-70.
8.Erkan Yılmaz, Sukru Gulec, Didem Torun, İbrahim Celalettin Haznedaroğlu, Nejat Akar. The effects of Ankaferd® Blood
Stopper on Transcription Factors in HUVEC and the Erythrocyte Protein Profile. 2011, Turkish J Hematol.; 28(4): 276-285.
9.Hu Z, Gulec S, Collins JF. Cross-species Comparison of Genomewide Gene Expression Profiles Reveals Induction of
Hypoxia-Inducible Factor-Responsive Genes in Iron-Deprived Intestinal Epithelial Cells. 2010, Am J Physiol Cell Physiol.;
299(5):C930-8.
10.Fikret Aydemir, Supak Jenkitkasemwong, Sukru Gulec, and Mitchell D. Knutson. Iron Loading Induces Ferroportin Gene
(Slc40a1) Transcription in Macrophage. 2009, The Journal of Nutrition; 139(3):434-8.
11.Tim Hofer, Emanuele Marzetti, Jinze Xu, Arnold Y. Seo, Sukru
Gulec, Mitchell D. Knutson, Christiaan Leeuwenburgh
and Esther E. Dupont-Versteegden. Increased RNA Oxidative Damage and Iron Content in Skeletal Muscle with Aging and
Tissue Atrophy. 2008, Experimental
Gerontology; 43(6):563-70.
Gulec, Ahmet Ruchan Akar, Nejat Akar. MEF2A Sequence Variants in Turkish Population. 2008, Clin Appl
Thrombosis Hemostasis; 14(4):465-7.
12.Sukru
13.Eroglu A, Gulec S, Akar N. Vascular Endothelial Growth Factor C936T Polymorphism in cancer patients with thrombosis.
2007, American J.Hematology;82(2):174.
14. Eroglu A, Gulec
S, Kurtman C, Cam R, Akar N. Vascular Endothelial Growth Factor 936 C/T Polymorphism in cancer
Patients. 2006, Annals of Oncology; 17(9):1467-8.
8.2. Uluslararası bilimsel toplantılarda sunulan ve bildiri kitabında
(Proceedings) basılan bildiriler
1.C. Doguer, S. Gulec and J.F. Collins. Development and Characterization of
Hephaestin Knockdown CaCo-2 Cells. Experimental Biology 2014, Sandiego, CA
(Poster Sunumu).
2.Sukru Gulec, Caglar Doguer, James F. Collins. Knock-Down of Menkes CopperTransporting ATPase (ATP7A) in Rat Intestinal Endothelial (IEC-6) Cells Increases
Ferroportin 1 (FPN1) Expression and Enhances Iron Transport. International BioIron
Society (IBIS) 2013, London, United Kingdom (Poster Sunumu)
Published: American Journal of Hematology, 88(5), E240-E241
3.S. Gulec, J. Collins, Silencing of the Menkes Copper-Transporting ATPase (Atp7a)
in Intestinal Epithelial Cells Impairs Cell Growth and Cell Cycle Control. Experimental
Biology 2013, Boston, MA (Sözlü Sunum).
Published: FASEB Journal, 27:223.5
4.S. Gulec, J. Collins. Iron Metabolism in a Rodent Model of Menkes Disease
(Brindled Mice). Experimental Biology 2013, Boston, MA (Poster Sunumu).
Published: FASEB Journal, 27:634.2
5.S. Gulec, J. Collins. Knock-Down of Atp7a Expression Reduces Hephaestin
Expression and Activity in A Rat Intestinal Epithelial Cell Line (IEC-6). Experimental
Biology 2013, Boston, MA (Poster Sunumu).
Published: FASEB Journal, 27:Ib293
6.S. Gulec, P. Ranganathan, Y. Lu, J. Collins. Physiologic Role of the Menkes
Copper ATPase (Atp7a) in Intestinal Iron Transport. Experimental Biology 2012, San
Diego, California (Sözlü Sunum ve Poster Sunumu).
Published: FASEB Journal, 26:641.2
7.James F. Collins, Sukru Gulec, Zihua Hu. Hypoxia Inducible Factor (HIF)
Responsive Genes Form the Core Transcriptional Response of the Intestinal
Epithelium During Iron Deficiency. Digestive Disease Week, New Orleans 2010, LA
(Poster Sunumu).
Published: Gastroenterology, 138(5), S-316
8.Afife Karabiyik, Erkan Yılmaz, Sukru Gulec, Ibrahim Haznedaroglu, Nejat Akar.
Reversible Actions of Ankaferd on EPCR and PAI-1 Inside Vascular Endothelial Cells
With and Without LPS. 21st International Congress on Thrombosis 2010, Milan, Italy
(Poster Sunumu).
9.H. Nam, S. Gulec, M.D. Knutson. Dietary iron deficiency increases Zip14
expression in rats. Experimental Biology 2008, San Diego, California (Poster
Sunumu).
Published: FASEB Journal, 22:155.4
10.H. Nam, N. Zhao, S. Gulec, J. P. Liuzzi, M.D. Knutson. Effects of Cellular Iron
Deficiency and Phlebotomy on Zip14 Expression. International BioIron Society (IBIS),
Biennial World Meeting 2007, Kyoto, Japan (Poster Sunumu).
Published: American Journal of Hematology, 82(6), 543-544
11.Gulec S, Akar R, Korkmaz O, Akar N. MEF2A sequence variants in Turkish
People. International Congress on Thrombosis 2006, Tel-Aviv, Israel (Sözlü Sunum).
8.3. Ulusal bilimsel toplantılarda sunulan ve bildiri kitabında basılan
bildiriler
1.Eroglu A, Gulec S, Kurtman C, Cam R, Akar N. Vascular Endothelial Growth
Factor 936 C/T Polymorphism in Cancer Patients. 6th National Thrombosis,
Homeostasis and Angiology Congress 2006, Izmir, Turkey (Poster Sunumu).
9. Projeler
Projenin Adı: Molecular Mechanism of Intestinal Metal Ion Transport During Iron
Deficiency
Projenin Yürütücüsü: James F. Collins
Projenin Dönemi: 2011- 2013
Destekleyen Kuruluş: National Institutes of Health (NIH) and Department of
National Institute of Diabetes and Digestive and Kidney Diseases (RO1DK07486702)
10. Bilimsel ve Mesleki Kuruluşlara Üyelikler
2010American Society for Nutrition (ASN)
11. Ödüller
Finalist, American Society for Nutrition’s Graduate Student Research Awards
Competition