FABAD J PHARM SCI OURNAL of ACEUTICAL ENCES

FABAD
JOURNAL of
PHARMACEUTICAL
SCIENCES
ISSN 1300-4182
www.fabad.org.tr
Volume: 37 • Issue: 3 • September 2012
An Official Journal of The Society of Pharmaceutical Sciences of Ankara (FABAD)
The Society of Pharmaceutical Sciences of Ankara (FABAD)
FABAD Journal of Pharmaceutical Sciences
Volume: 37 Issue: 3 September 2012
Publisher
Nesrin GÖKHAN KELEKÇI
(Hacettepe University, Ankara, Turkey)
Editor-in-Chief
Didem DELIORMAN ORHAN
(Gazi University, Ankara, Turkey)
Associate Editors
Nilüfer ORHAN
Ahmet Oğuz ADA
Aysel BERKKAN
İ. İrem ÇANKAYA
(Gazi University, Ankara, Turkey)
(Ankara University, Ankara, Turkey)
(Gazi University, Ankara, Turkey)
(Hacettepe University, Ankara, Turkey)
Editorial Board
Nurettin ABACIOĞLU
Zeliha AKDEMİR
Asuman BOZKIR
Ünsal ÇALIŞ
Erdal DİNÇ
Benay Can EKE
Fatma GÜMÜŞ
İlhan GÜRBÜZ
Süeda HEKİMOĞLU
Blanca LAFFON
Levent ÖNER
A. Yekta ÖZER
Sibel ÖZKAN
Yalçın ÖZKAN
Tanju ÖZÇELİKAY
Nurten ÖZDEMİR
Rita De PASQUALE
Nadja Souza PINTO
Selma SARAÇ
Sevgi ŞAR
Uğur TAMER
Maria Fernanda TAVIANO
João Paulo TEIXEIRA
Meral TUNÇBİLEK
Nilüfer TURAN
Eva Maria Munoz VALENTINE
Beata WALCZAK
Sulhiye YILDIZ
Serhat Ali ARIKAN
(Gazi University, Ankara, Turkey)
(Hacettepe University, Ankara, Turkey)
(Ankara University, Ankara, Turkey)
(Hacettepe University, Ankara, Turkey)
(Ankara University, Ankara, Turkey)
(Ankara University, Ankara, Turkey)
(Gazi University, Ankara, Turkey)
(Gazi University, Ankara, Turkey)
(Hacettepe University, Ankara, Turkey)
(University of A Coruña, A Coruna, Spain)
(Hacettepe University, Ankara, Turkey)
(Hacettepe University, Ankara, Turkey)
(Ankara University, Ankara, Turkey)
(Gulhane Military Medical Academy, Ankara, Turkey)
(Ankara University, Ankara, Turkey)
(Ankara University, Ankara, Turkey)
(University of Messina, Messina, Italy)
(University of Sao Paulo, Sao Paula, Brazil)
(Hacettepe University, Ankara, Turkey)
(Ankara University, Ankara, Turkey)
(Gazi University, Ankara, Turkey)
(University of Messina, Messina, Italy)
(National Institute of Health, Porto, Portekiz)
(Ankara University, Ankara, Turkey)
(Gazi University, Ankara, Turkey)
(Univarsidade de Santiago de Compostela, Spain)
(University of Silesia, Poland)
(Ankara University, Ankara, Turkey)
(Language Editor, Ankara, Turkey)
The FABAD Journal of Pharmaceutical Sciences is published quarterly by the
Society of Pharmaceutical Sciences of Ankara (FABAD)
All expressions of opinion and statements of supposed facts appearing in articles and / or advertisiments carried in this
journal are published on the responsibility of the author and / or advertiser, and are not to be regarded those of the Society of Pharmaceutical Sciences of Ankara. The manuscript submitted to the Journal has the requirement of not being
published previously and has not been submitted elsewhere. Manuscript should bu prepared in accordance with the
requirements specified as in the back cover. The submission of the manuscript to the Journal is not a condition for acceptance; articles are accepted or rejected on merit alone. The Journal is distributed to the members only. Nonmembers can
obtain the journal by a donation to FABAD. All rights reserved. Neither this work nor any part may be reproduced or
transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information
storage and retrieval systems without written permission from FABAD Journal of Pharmaceutical Sciences.
The FABAD Journal of Pharmaceutical Sciences is indexed in Chemical Abstracts,
Analytical Abstracts, International Pharmaceutical Abstracts, Excerpta Medica (EMBASE),
ISI Master Journal List, Scopus and Proquest, Akademik Dizin
All manuscripts and editorial correspondences should be sent via e-mail to Didem Deliorman Orhan
(Editor-in-Chief ): [email protected]
The payment of donation has to be sent to the bank Account Number given below:
Türkiye İş Bankası, Gazi Mahallesi Şubesi, Ankara, Account number: 4286 304400 201434
CONTENTS
Research Articles
123 Antioxidant Capacity and Total Phenol Contents of Bifora radians Bieb.
Ayşegül KÖROĞLU, Muhammed Mesud HÜRKUL, Özen ÖZBAY
129 The Relationship Between Cadmium Contents of Tobacco and Their Ash in Cigarettes
Marketed Under Different Brands
Beril KADIOĞLU, Esin NALTEKIN, Mohammad CHAREHSAZ, Hande SIPAHI,
Buğra SOYKUT, Ahmet AYDIN
133 A Validated RP-HPLC Method for the Determination of Bendamustine hydrochloride
in Tablet Dosage Form using Gemcitabine hydrochloride as Internal Standard
Kiran Kumar KATARE, Venkata Nadh RATNAKARAM, Nagoji K.E.V.
141 Spectrophotometric Assay of Diethylcarbamazine citrate using Folin-Ciocalteu
Phenol Reagent
Nagaraju SWAMY, Kudige Nagaraj PRAHANTH, Kanakapura BASAVAIAH,
Kanakapura BASAVAIAH VINAY
151 Analgesic and antioxidant activity of some Echium species wild growing in Turkey
Nuraniye ERUYGUR, Gülderen YILMAZ, Osman ÜSTÜN
161 Antioxidant capacities, ascorbic acid and total phenol contents of the plants sold as
Rose hip in Turkey
Didem DELIORMAN ORHAN, Özlem ÖZLÜK, Sanem HOŞBAŞ COŞKUN
INSTRUCTIONS FOR AUTHORS
All new manuscripts and correspondence regarding editorial matters should be addressed to the Editor-in-Chief, Prof. Dr. Didem Deliorman
Orhan
Prof.Dr. Didem Deliorman Orhan
FABAD J Pharm Sci
Editor-in-Chief
Phone: +90 3122023173
Fax: +90 312 2235018
E-mail: [email protected]
SCOPE OF THE JOURNAL
The journal publishes original, innovative research articles, review articles, short communications, scientific reports in all fields of pharmaceutical
and related health sciences.
It is recommended that all articles do not exceed a total of 15 double spaced pages including references, tables, figure legends and figures using font
size 12. Review articles are allowed up to 25 pages. The publication language is English.
CONFLICT OF INTEREST
All authors are requested to disclose any actual or potential conflict of interest including any financial, personal or other relationships with other
people or organizations within three years of beginning the submitted work that could inappropriately influence, or be perceived to influence, their
work.
DECLARATION OF SUBMISSION
Submission of an article implies that the work described has not been published previously (except in the form of an abstract or as part of a published lecture or academic thesis), that it is not under consideration for publication elsewhere, that its publication is approved by all authors and
tacitly or explicitly by the responsible authorities where the work was carried out, and that, if accepted, it will not be published elsewhere in the
same form, in English or in any other language, without the written consent of the copyright-holder.
SUBMISSION
Submission to this journal proceeds only by e-mail to the editor ([email protected]). All correspondences, including notification of the
Editor’s decision and requests for revision takes place by e-mail.
Research Articles
Articles in all fields of pharmaceutical and related health sciences (physical, chemical, biological, medical, dental, social, etc.), presenting an original research could be consider for publication.
Scientific Reviews
An updated comprehensive review, with sufficient number of scientific articles including original paper(s) of the author(s) on a subject, evaluating
and discussing the results could be consider for publication. Short Communications
Rapid announcement of the results of a continuing research, not exceeding two printed pages can be submitted as a short communication.
Scientific Reports
a) Articles dealing with important scientific pharmaceutical events in Turkey and in the world,
b) Recent equipment and materials,
c) Short information and reports on the pharmaceutical congresses, conferences, symposia, etc.,
d) English summaries of Ph.D. theses in pharmaceutical sciences,
e) Reviews of scientific books in pharmaceutical sciences,
f ) Reviews on recently published scientific journals, etc. can be submitted as a short communication.
Preparation of manuscripts
1. Text should be typed double spaced in A4 format with a margin of 2 cm on each side of the page using a word processor, MS Office for Windows.
2. Following the article title, author names and affiliations should be stated. All affiliations should be stated with a lower-case superscript letter.
Provide the full postal address of each affiliation, including the country name, and e-mail address of the corresponding author.
3. A cover page should be provided with the title of article, author name and affiliations (including fax, telephone, e-mail addresses) of the author
to whom all correspondence should be directed. Manuscripts submitted should have a separate letter including the signatures of each author.
4. The Declaration of Helsinki as amended in Seoul 2008 for humans, and the European Community guidelines and Turkish Official guidelines as
accepted principles for the use of experimental animals, must be also adhered to.
5. Sections of the manuscripts should adhere to the following sequence:
Summary
It should be written in Turkish and English, not exceeding 200 words, title and keywords should be given in both languages. List of keywords (maximum 5) should be provided under the summaries. The aim of the study, methods, results and conclusion should be described briefly.
Introduction
The objective of the work should be stated and an adequate background provided, avoiding a detailed literature survey or a summary of the results.
Material and methods
Sufficient detail should be provided to allow the work to be reproduced. Methods already published should be indicated by a reference: only relevant modifications should be described.
Results
Results should be clear and concise.
Discussion
This should explore the significance of the results of the work, not repeat them. A combined Results and Discussion section is often appropriate.
Avoid extensive citations and discussion of published literature.
Conclusions
The main conclusions of the study may be presented in a short Conclusions section, which may stand alone or form a subsection of a Discussion or
Results and Discussion section.
References
The reference numbers should be given in parentheses. If more than one reference is cited at a time, they should be listed by date, starting with the
earliest.
Articles:
1. Stalcup AM, Chang SC, Armstrong DW, Pitha J. (s)-2-Hydroxypropyl-ßcyclodextrin, a new chiral stationary phase for reversed–phase liquid
chromatography. J Chromatogr A 513: 181-194, 1990.
Books:
2. Van de Waterbeemd H. Quantitative approaches to structure-activity relationships. In: Wermuth CG, editor. The practice of medicinal chemistry.
4th ed. Great Britain: Academic Press; 2001. p. 367-89. Watson, DG. Pharmaceutical analysis. 1st ed. Chine: Churchill Livingstone; 1999.
Dissertations:
3. Karakurt A. Studies on synthesis, enantiomeric separation, anticonvulsant and antimicrobial activities of some new 2-acetylnaphthalene derivatives
[dissertation]. Ankara (Turkey): Hacettepe University Institute of Health Sciences; 2004.
Patents:
4. Larsen CE, Trip R, Johnson CR, inventors; Novoste Corporation, assignee. Methods for procedures related to the electrophysiology of the heart.
US patent 5,529,067. 1995 Jun 25.
Electronic articles:
Morse SS. Factors in the emergence of infectious diseases. Emerg Infect Dis {serial online] 1995 Jan-Mar [cited 1996 Jun 5]; 1(1):[24 screens].
Available from: URL: http://www.cdc.gov/ncidod/EID/eid.htm
Figures and graphics
Figures, graphics and photographs should be in TIFF or JPEG format submitted as a separate file. Figure legends should be written on a separate
page.
Tables
Tables should be submitted on a separate page.